Copines make up a multigene family of calcium-dependent, phospholipid-binding proteins. Copine proteins consists of two C2 domains at the N terminus followed by an "A domain" similar to the von Willebrand-Integrin A domain. Mutant studies of...
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Copines are a group of calcium-dependent membrane binding proteins found in many organisms, including humans. We elucidated the function of these proteins by studying their role in the development of Dictyostelium discoideum, a single-celled...